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1

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

Gerasimos P. Sykiotis, Dirk Bohmann

Journal:

Developmental Cell

Year:

2008

Language:

english

File:

PDF, 1.17 MB

english, 2008

2

Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial

Chartoumpekis, Dionysios V., Ziros, Panos G., Chen, Jian-Guo, Groopman, John D., Kensler, Thomas W., Sykiotis, Gerasimos P.

Journal:

Food and Chemical Toxicology

Year:

2019

Language:

english

File:

PDF, 836 KB

english, 2019

3

Impact of Antioxidant Natural Compounds on the Thyroid Gland and Implication of the Keap1/Nrf2 Signaling Pathway

Paunkov, Ana, Chartoumpekis, Dionysios V., Ziros, Panos G., Chondrogianni, Niki, Kensler, Thomas W., Sykiotis, Gerasimos P.

Journal:

Current Pharmaceutical Design

Year:

2019

Language:

english

File:

PDF, 2.51 MB

english, 2019

4

The Bethesda System for Reporting Thyroid Cytopathology explained for practitioners: Frequently Asked Questions

Bongiovanni, Massimo, PAPADAKIS, GEORGIOS E., Rouiller, Nathalie, MARINO, LAURA, LAMINE, FAIZA, Bisig, Bettina, Ziadi, Sonia, SYKIOTIS, GERASIMOS P

Journal:

Year:

2018

Language:

english

File:

PDF, 2.84 MB

english, 2018

5

Congenital Idiopathic Hypogonadotropic Hypogonadism: Evidence of Defects in the Hypothalamus, Pituitary, and Testes

Sykiotis, Gerasimos P., Hoang, Xuan-Huong, Avbelj, Magdalena, Hayes, Frances J., Thambundit, Apisadaporn, Dwyer, Andrew, Au, Margaret, Plummer, Lacey, Crowley, William F., Pitteloud, Nelly

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

6

Subclinical hypothyroidism: new trials, old caveats

Lamine, Faiza, De Giorgi, Sara, Marino, Laura, Michalaki, Marina, Sykiotis, Gerasimos P.

Journal:

Year:

2018

Language:

english

File:

PDF, 388 KB

english, 2018

7

Uptake of 99mTc-MIBI by Sclerosing Pneumocytoma Raising a False Suspicion of Metastasis From Medullary Thyroid Carcinoma

Papadakis, Georgios E, Tabotta, Flavian, Levotanec, Igor, Gonzalez, Michel, Prior, John O, La Rosa, Stefano, Sykiotis, Gerasimos P

Journal:

Journal of the Endocrine Society

Year:

2018

Language:

english

File:

PDF, 778 KB

english, 2018

8

Impact of Antioxidant Natural Compounds on the Thyroid Gland and Implication of the Keap1/Nrf2 Signaling Pathway

Paunkov, Ana, Chartoumpekis, Dionysios V., Ziros, Panos G., Chondrogianni, Niki, Kensler, Thomas W., Sykiotis, Gerasimos P.

Journal:

Current Pharmaceutical Design

Year:

2019

File:

PDF, 2.51 MB

2019

9

Selective modulation of postmenopausal women : Cutting the Gordian knot of hormone replacement therapy with breast carcinoma

Evanthia Diamanti-Kandarakis, Gerasimos P. Sykiotis, Athanasios G. Papavassiliou

Journal:

Year:

2003

Language:

english

File:

PDF, 101 KB

english, 2003

10

The α2Badrenergic receptor deletion/insertion polymorphism in morbid obesity

Gerasimos P. Sykiotis, Eftihia Polyzogopoulou, Neoklis A. Georgopoulos, Georgia Trakada, Kostas Spyropoulos, Fotios Kalfarentzos, Athanasios G. Papavassiliou, Apostolos G. Vagenakis, Christodoulos S.

Journal:

Clinical Autonomic Research

Year:

2003

Language:

english

File:

PDF, 201 KB

english, 2003

11

Hippocrates and Genomic Medicine

Gerasimos P. Sykiotis, George D. Kalliolias, Athanasios G. Papavassiliou

Journal:

Archives of Medical Research

Year:

2006

Language:

english

File:

PDF, 73 KB

english, 2006

12

Gemcitabine and pegylated liposomal doxorubicin alternating with cisplatin plus cyclophosphamide in platinum refractory/resistant, paclitaxel-pretreated, ovarian carcinoma

Dimitrios Pectasides, Nicolaos Xiros, George Papaxoinis, Gerasimos Aravantinos, Constantinos Sykiotis, Erini Pectasides, Amanda Psyrri, Anna Koumarianou, Asimina Gaglia, Panayiotis Gouveris, Theofanis

Journal:

Gynecologic Oncology

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

13

Molecular medicine: a lifetime of learning, teaching and caring

Gerasimos P. Sykiotis, Athanasios G. Papavassiliou

Journal:

Trends in Molecular Medicine

Year:

2005

Language:

english

File:

PDF, 56 KB

english, 2005

14

Functional significance of the thyrotropin receptor germline polymorphism D727E

Gerasimos P Sykiotis, Susanne Neumann, Neoklis A Georgopoulos, Argyro Sgourou, Adamantia Papachatzopoulou, Kostas B Markou, Venetsana Kyriazopoulou, Ralf Paschke, Apostolos G Vagenakis, Athanasios G P

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 172 KB

english, 2003

15

Clinical Experience with Levonorgestrel Subdermal Implants (Norplant®)1 for Long-Term Contraception

Emanuel Cardamakis, Neoklis A. Georgopoulos, Athanassios P. Pappas, Andreas Fotopoulos, Gerasimos P. Sykiotis, Dr Vassilios A. Tzingounis

Journal:

Clinical Drug Investigation

Year:

2001

Language:

english

File:

PDF, 128 KB

english, 2001

16

Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 Are Identified in Individuals with Congenital Hypogonadotropic Hypogonadism

Miraoui, Hichem, Dwyer, Andrew A., Sykiotis, Gerasimos P., Plummer, Lacey, Chung, Wilson, Feng, Bihua, Beenken, Andrew, Clarke, Jeff, Pers, Tune H., Dworzynski, Piotr, Keefe, Kimberley, Niedziela, Mar

Journal:

The American Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 1.41 MB

english, 2013

17

A Genetic Basis for Functional Hypothalamic Amenorrhea

Caronia, Lisa M., Martin, Cecilia, Welt, Corrine K., Sykiotis, Gerasimos P., Quinton, Richard, Thambundit, Apisadaporn, Avbelj, Magdalena, Dhruvakumar, Sadhana, Plummer, Lacey, Hughes, Virginia A., Se

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 952 KB

english, 2011

18

Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes

Rahman, Mohammed Mahidur, Sykiotis, Gerasimos P., Nishimura, Mayuko, Bodmer, Rolf, Bohmann, Dirk

Journal:

Year:

2013

Language:

english

File:

PDF, 669 KB

english, 2013

19

Differential regulation of the proteasome and of antioxidant responses during aging in the somatic tissues and the gonads of Drosophila

Tsakiri, Eleni N., Sykiotis, Gerasimos P., Papassideri, Issidora S., Terpos, Evangelos, Dimopoulos, Meletios A., Gorgoulis, Vassilis G., Bohmann, Dirk, Trougakos, Ioannis P.

Journal:

Free Radical Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 71 KB

english, 2013

20

Trial of Recombinant Follicle-Stimulating Hormone Pretreatment for GnRH-Induced Fertility in Patients with Congenital Hypogonadotropic Hypogonadism

Dwyer, Andrew A., Sykiotis, Gerasimos P., Hayes, Frances J., Boepple, Paul A., Lee, Hang, Loughlin, Kevin R., Dym, Martin, Sluss, Patrick M., Crowley, William F., Pitteloud, Nelly

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2013

Language:

english

File:

PDF, 1008 KB

english, 2013

21

Congenital hypogonadotropic hypogonadism with split hand/foot malformation: a clinical entity with a high frequency of FGFR1 mutations

Villanueva, Carine, Jacobson-Dickman, Elka, Xu, Cheng, Manouvrier, Sylvie, Dwyer, Andrew A., Sykiotis, Gerasimos P., Beenken, Andrew, Liu, Yang, Tommiska, Johanna, Hu, Youli, Tiosano, Dov, Gerard, Mar

Journal:

Genetics in Medicine

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

22

Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging

Tsakiri, Eleni N., Sykiotis, Gerasimos P., Papassideri, Issidora S., Terpos, Evangelos, Dimopoulos, Meletios A., Gorgoulis, Vassilis G., Bohmann, Dirk, Trougakos, Ioannis P.

Journal:

Year:

2013

Language:

english

File:

PDF, 519 KB

english, 2013

23

Targeting the nerve growth factor network in Alzheimer’s disease

Sykiotis, Gerasimos P, Papavassiliou, Athanasios G

Journal:

Expert Opinion on Investigational Drugs

Year:

2007

Language:

english

File:

PDF, 97 KB

english, 2007

24

Genetic Overlap in Kallmann Syndrome, Combined Pituitary Hormone Deficiency, and Septo-Optic Dysplasia

Raivio, Taneli, Avbelj, Magdalena, McCabe, Mark J., Romero, Christopher J., Dwyer, Andrew A., Tommiska, Johanna, Sykiotis, Gerasimos P., Gregory, Louise C., Diaczok, Daniel, Tziaferi, Vaitsa, Elting,

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2012

Language:

english

File:

PDF, 521 KB

english, 2012

25

Serine Phosphorylation of Insulin Receptor Substrate-1: A Novel Target for the Reversal of Insulin Resistance

Sykiotis, Gerasimos P., Papavassiliou, Athanasios G.

Journal:

Molecular Endocrinology

Year:

2001

Language:

english

File:

PDF, 146 KB

english, 2001

26

Apoptosis: the suicide solution in cancer treatment and chemoprevention

Sykiotis, Gerasimos P, Papavassiliou, Athanasios G

Journal:

Expert Opinion on Investigational Drugs

Year:

2006

Language:

english

File:

PDF, 298 KB

english, 2006

27

A Genetic Basis for Functional Hypothalamic Amenorrhea

Caronia, Lisa M., Martin, Cecilia, Welt, Corrine K., Sykiotis, Gerasimos P., Quinton, Richard, Thambundit, Apisadaporn, Avbelj, Magdalena, Dhruvakumar, Sadhana, Plummer, Lacey, Hughes, Virginia A., Se

Journal:

Obstetric and Gynecologic Survey

Year:

2011

Language:

english

File:

PDF, 350 KB

english, 2011

28

Pharmacogenetic Principles in the Hippocratic Writings

Sykiotis, Gerasimos P., Kalliolias, George D., Papavassiliou, Athanasios G.

Journal:

Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 56 KB

english, 2005

29

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

Sykiotis, Gerasimos P, Habeos, Ioannis G, Samuelson, Andrew V, Bohmann, Dirk

Journal:

Current Opinion in Clinical Nutrition & Metabolic Care

Year:

2011

Language:

english

File:

PDF, 276 KB

english, 2011

30

Papillary thyroid carcinoma with nodular fasciitis-like stroma and β-catenin mutations should be renamed papillary thyroid carcinoma with desmoid-type fibromatosis

Rebecchini, Caterina, Nobile, Antoine, Piana, Simonetta, Sarro, Rossella, Bisig, Bettina, Gerasimos, Sykiotis P, Saglietti, Chiara, Matter, Maurice, Marino, Laura, Bongiovanni, Massimo

Journal:

Modern Pathology

Year:

2016

Language:

english

File:

PDF, 4.35 MB

english, 2016

31

Columnar cell variant of papillary thyroid carcinoma: Cytomorphological characteristics of 11 cases with histological correlation and literature review

Bongiovanni, Massimo, Mermod, Maxime, Canberk, Sule, Saglietti, Chiara, Sykiotis, Gerasimos P., Pusztaszeri, Marc, Ragazzi, Moira, Mazzucchelli, Luca, Giovanella, Luca, Piana, Simonetta

Journal:

Cancer Cytopathology

Year:

2017

Language:

english

File:

PDF, 643 KB

english, 2017

32

Very low expression of PD-L1 in medullary thyroid carcinoma

Bongiovanni, Massimo, Rebecchini, Caterina, Saglietti, Chiara, Bulliard, Jean-Luc, Marino, Laura, De Leval, Laurence, Sykiotis, Gerasimos P.

Journal:

Endocrine Related Cancer

Year:

2017

Language:

english

File:

PDF, 466 KB

english, 2017

33

DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development

Bouilly, Justine, Messina, Andrea, Papadakis, Georgios, Cassatella, Daniele, Xu, Cheng, Acierno, James S, Tata, Brooke, Sykiotis, Gerasimos, Santini, Sara, Sidis, Yisrael, Elowe-Gruau, Eglantine, Phan

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 1.14 MB

english, 2017

34

Congenital Hypogonadotropic Hypogonadism and Constitutional Delay of Growth and Puberty Have Distinct Genetic Architectures

Cassatella, Daniele, Howard, Sasha, Acierno, James, Xu, Cheng, Papadakis, Georgios, Santoni, Federico A., Dwyer, Andrew A., Santini, Sara, Sykiotis, Gerasimos, Chambion, Caroline, Meylan, Jenny, Marin

Journal:

European Journal of Endocrinology

Year:

2018

Language:

english

File:

PDF, 4.78 MB

english, 2018

35

Hepatic Gene Expression Profiling in Nrf2 Knockout Mice after Long-Term High-Fat Diet-Induced Obesity

Chartoumpekis, Dionysios V., Ziros, Panos G., Zaravinos, Apostolos, Iskrenova, Ralitsa P., Psyrogiannis, Agathoklis I., Kyriazopoulou, Venetsana E., Sykiotis, Gerasimos P., Habeos, Ioannis G.

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2013

Language:

english

File:

PDF, 1.48 MB

english, 2013

36

Redox Status and Proteostasis in Ageing and Disease

Rizzi, Federica, Trougakos, Ioannis P., Pintus, Gianfranco, Sykiotis, Gerasimos P.

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

37

Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

Blum, Manuel R, Gencer, Baris, Adam, Luise, Feller, Martin, Collet, Tinh-Hai, da Costa, Bruno R, Moutzouri, Elisavet, Dopheide, Jörn, Depairon, Michèle, Sykiotis, Gerasimos P, Kearney, Patricia, Gusse

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2018

Language:

english

File:

PDF, 1.05 MB

english, 2018

38

Raman spectroscopy for the preoperative diagnosis of thyroid cancer and its subtypes: an in vitro proof-of-concept study

O'Dea, Declan, Bongiovanni, Massimo, Sykiotis, Gerasimos P., Ziros, Panos G., Meade, Aidan D., Lyng, Fiona M., Malkin, Alison

Journal:

Year:

2018

Language:

english

File:

PDF, 963 KB

english, 2018

39

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

Tsakiri, Eleni N., Gumeni, Sentiljana, Iliaki, Kalliopi K., Benaki, Dimitra, Vougas, Konstantinos, Sykiotis, Gerasimos P., Gorgoulis, Vassilis G., Mikros, Emmanuel, Scorrano, Luca, Trougakos, Ioannis

Journal:

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

40

New therapeutic perspectives to manage refractory immune checkpoint-related toxicities

Martins, Filipe, Sykiotis, Gerasimos P, Maillard, Michel, Fraga, Montserrat, Ribi, Camillo, Kuntzer, Thierry, Michielin, Olivier, Peters, Solange, Coukos, Georges, Spertini, Francois, Thompson, John A

Journal:

The Lancet Oncology

Year:

2019

Language:

english

File:

PDF, 714 KB

english, 2019

41

Expression of Prox1 in Medullary Thyroid Carcinoma Is Associated with Chromogranin A and Calcitonin Expression and with Ki67 Proliferative Index, but Not with Prognosis

Saglietti, Chiara, La Rosa, Stefano, Sykiotis, Gerasimos P., Letovanec, Igor, Bulliard, Jean-Luc, Piana, Simonetta, Mermod, Maxime, Petrova, Tatiana, Uccella, Silvia, Sessa, Fausto, Bongiovanni, Massi

Journal:

Endocrine Pathology

Year:

2019

Language:

english

File:

PDF, 5.51 MB

english, 2019

42

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

Martins, Filipe, Sofiya, Latifyan, Sykiotis, Gerasimos P., Lamine, Faiza, Maillard, Michel, Fraga, Montserrat, Shabafrouz, Keyvan, Ribi, Camillo, Cairoli, Anne, Guex-Crosier, Yan, Kuntzer, Thierry, Mi

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2019

Language:

english

File:

PDF, 1.81 MB

english, 2019

43

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

Martins, Filipe, Sofiya, Latifyan, Sykiotis, Gerasimos P., Lamine, Faiza, Maillard, Michel, Fraga, Montserrat, Shabafrouz, Keyvan, Ribi, Camillo, Cairoli, Anne, Guex-Crosier, Yan, Kuntzer, Thierry, Mi

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2019

File:

PDF, 1.81 MB

2019

44

Approach to cytological indeterminate thyroid nodules

Bongiovanni, Massimo, Bellevicine, Claudio, Troncone, Giancarlo, Sykiotis, Gerasimos P.

Journal:

Year:

2019

Language:

english

File:

PDF, 728 KB

english, 2019

45

A Bibliometric Review of the Keap1/Nrf2 Pathway and its Related Antioxidant Compounds

Paunkov, Ana, Chartoumpekis, Dionysios V., Ziros, Panos G., Sykiotis, Gerasimos P.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.70 MB

english, 2019

46

The dietary triterpenoid 18α–Glycyrrhetinic acid protects from MMC-induced genotoxicity through the ERK/Nrf2 pathway

Lefaki, Maria, Papaevgeniou, Nikoletta, Tur, Josep A., Vorgias, Constantinos E., Sykiotis, Gerasimos P., Chondrogianni, Niki

Journal:

Year:

2020

Language:

english

File:

PDF, 1.40 MB

english, 2020

47

The dietary triterpenoid 18α–Glycyrrhetinic acid protects from MMC-induced genotoxicity through the ERK/Nrf2 pathway

Lefaki, Maria, Papaevgeniou, Nikoletta, Tur, Josep A., Vorgias, Constantinos E., Sykiotis, Gerasimos P., Chondrogianni, Niki

Journal:

Year:

2020

File:

PDF, 1.40 MB

2020

48

Rare and common genetic variations in the Keap1/Nrf2 antioxidant response pathway impact thyroglobulin gene expression and circulating levels, respectively

Matana, Antonela, Ziros, Panos G., Chartoumpekis, Dionysios V., Renaud, Cedric O., Polašek, Ozren, Hayward, Caroline, Zemunik, Tatijana, Sykiotis, Gerasimos P.

Journal:

Biochemical Pharmacology

Year:

2019

Language:

english

File:

PDF, 617 KB

english, 2019

49

Macrofollicular variant of follicular thyroid carcinoma: a rare, underappreciated pitfall in the diagnosis of thyroid carcinoma

Bongiovanni, Massimo, SYKIOTIS, GERASIMOS P, La Rosa, Stefano, Bisig, Bettina, Trimech, Mounir, Missiaglia, Edoardo, Gremaud, Magali, Salvatori-Chappuis, Vilma, De Vito, Claudio, Sciarra, Amedeo, Foul

Journal:

Year:

2019

File:

PDF, 1.11 MB

2019

50

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

Tsakiri, Eleni, Gumeni, Sentiljana, Benaki, Dimitra, Vougas, Konstantinos, Sykiotis, Gerasimos, Gorgoulis, Vassilis, Fokialakis, Nikolas, Quazzani, Jamal, Mikros, Emmanuel, Scorrano, Luca, Trougakos,

Journal:

Free Radical Biology and Medicine

Year:

2018

File:

PDF, 54 KB

2018

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